Several Au deposits in Guizhou Province, southwest China, described as being similar to the highly productive Carlintype gold deposits in northern Nevada, USA, were examined to identify similarities and differences between the two districts. Samples were collected along transects from lowto highgrade rock, where possible, and from stockpiles at the Shuiyindong, Zimudang, Taipingdong, Yata and Jinfeng (formerly Lannigou) deposits. Methods used to examine ore and alteration minerals included handsample description; reflectance spectroscopy using an ASD Terraspec spectrometer; analyses of hand samples by carbonate staining with Alizaren red and potassium ferricyanide; transmitted and reflected light petrography; chemical analyses, mineral identification, and imaging using a JEOL JSM5610 scanning electron microscope; and quantitative chemical analyses using a JEOL JXA8900 electron probe microanalyzer. Geochemical analyses of hand samples for 52 elements were done by ALS Chemex. Results indicate both similarities and differences between the two districts. Both districts have similar geologic histories, and deposits at both locations appear to have formed as a result of similar tectonic events, though the district in southwest China lacks evidence of coeval felsic igneous activity; however, the orestage minerals and the fluids that produced the minerals and deposits have some significant differences. The Nevada deposits were dominated by fluidrock reaction in which host rock Fe was sulfidized to form Aubearing pyrite. Although ore fluids sulfidized host rock Fe in the Guizhou deposits, the timing of Fe metasomatism is unknown, so whether the deposits formed in response to sulfidation or pyritization is unclear. Fluidrock reaction between an acidic, aqueous fluid and highly reactive calcareous rocks in Nevada caused extensive decarbonatization of host rocks, jasperoid replacement of carbonate minerals, and alteration of silty rock components to illite and kaolinite. In Guizhou, CO2bearing ore fluids with temperatures and pressures approaching 100 ℃ and 500 bars greater than temperatures and pressures determined for ore fluids in the Nevada deposits, deposited Aubearing pyrite. In examined Guizhou deposits these fluids carbonatized host rocks and formed both replacement and openspacefilling ore. The fluids, which may have been immiscible, were sufficiently overpressured to fracture wall rocks and to create significant open space filled by vein quartz. While deposit architecture, tectonic setting, and host rocks in Guizhou are quite similar to northern Nevada, ore and alteration minerals suggest that oreforming processes in examined Guizhou deposits have important similarities to processes associated with formation of orogenic Au systems. The Guizhou deposits display characteristics of both Carlin-type and orogenic systems, perhaps indicating formation at conditions somewhat intermediate to conditions for Carlintype deposits and orogenic systems.